Hot Phillys, Fresh Seafood, Friendly Service.
Crafted
With Love in the Heart of South Carolina
At Deno’s Subs & Seafood in Columbia, SC, we’re passionate about serving up fresh, flavorful meals that keep our customers coming back. From our mouthwatering Philly Steak Subs to our crisp, satisfying Greek Salads and hearty Chicken Combos, every dish is made with quality ingredients and care.
Whether you’re grabbing a quick lunch, picking up dinner for the family, or stopping in while traveling through town, you can count on friendly service and food made fresh to order. We take pride in offering generous portions, bold flavors, and a welcoming atmosphere that makes every visit enjoyable.
Stop by Deno’s Subs & Seafood and taste the difference for yourself, great food, great service, every time.
Fresh Ingredients
Quality Meats
Quick Service
Yummy
Menu
Unmatched Flavors
11” Philly Steak
Grilled w/ onions, green pepper, mushroom
w/ mayo, lettuce, tomatoes & provolone cheese
$10.99
11” Fish Sub
Mayo, pickles, lettuce, tomatoes, onions & add cheese for .50 cents
$10.99
11” Chicken Parm Sub
Fried or grilled w/ Marianiara Sauce & Provolone cheese
$12.99
CheeseBurger
Mayo, ketchup, mustard, pickles, lettuce, tomatoes, onions, & American cheese
$6.99
Traditional Gyro
Grilled onion, tomatoes, & tzatziki
Add feta for .50 cents
$9.99
Veggie Pita or Sub
Grilled w/ onions, green pepper, mushroom, banana pepper, olives, w/ mayo, lettuce, tomatoes & provolone cheese
$7.99
Reviews
Deno’s Subs & Seafood on St Andrews Rd is one of my favorite lunch spots in Columbia. The Philly steak sub was hot, fresh, and loaded with flavor. The service was fast and friendly, and my order was ready right on time. Perfect place for takeout if you’re in the area!
Best subs in Columbia! I ordered the Philly steak and fries, and everything was made fresh to order. The staff was super friendly, and the location on St Andrews Rd makes it a quick stop for lunch. You can’t beat the quality and value here.
If you’re looking for great seafood in Columbia, SC, this is the place to go. The shrimp and fish were cooked perfectly, and the portions were generous. It’s conveniently located on St Andrews Rd, so it’s easy to swing by and grab dinner. Definitely coming bac
Stopped by Deno’s while traveling through Columbia and was impressed! The large Greek salad was fresh and packed with toppings, and my husband loved his chicken combo. Great food, clean restaurant, and very welcoming staff. Highly recommend if you’re nearby.